منابع مشابه
Molecular Pathogenesis of Vibrio vulnificus.
Vibrio vulnificus is an opportunistic pathogen of humans that has the capability of causing rare, yet devastating disease. The bacteria are naturally present in estuarine environments and frequently contaminate seafoods. Within days of consuming uncooked, contaminated seafood, predisposed individuals can succumb to sepsis. Additionally, in otherwise healthy people, V. vulnificus causes wound in...
متن کاملVibrio vulnificus: disease and pathogenesis.
6 Melissa K. Jones and James D. Oliver 1 7 8 Department of Biology 9 10 University of North Carolina at Charlotte 11 12 Charlotte, NC 28223 13 14 15 16 17 18 19 20 21 22 1 To whom correspondence should be addressed 23 email: [email protected] 24 tel: 704-687-8516 25 fax: 206-350-1385 26 Copyright © 2009, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserv...
متن کاملVibrio vulnificus infection: clinical manifestations, pathogenesis, and antimicrobial therapy.
There has been a dramatic increase in the number of reported cases of infection due to Vibrio vulnificus in Taiwan. Although the organism has been etiologically implicated in a variety of clinical syndromes, most cases of V. vulnificus infection are categorized as primary bacteremia, skin and soft tissue infection. The mortality was up to 50% in septic patients, most of them dying within 48 h o...
متن کاملPathogenesis of infection by clinical and environmental strains of Vibrio vulnificus in iron-dextran-treated mice.
Vibrio vulnificus is an opportunistic pathogen that contaminates oysters harvested from the Gulf of Mexico. In humans with compromising conditions, especially excess levels of iron in plasma and tissues, consumption of contaminated seafood or exposure of wounds to contaminated water can lead to systemic infection and disfiguring skin infection with extremely high mortality. V. vulnificus-associ...
متن کاملRegulatory Characteristics of Vibrio vulnificus gbpA Gene Encoding a Mucin-binding Protein Essential for Pathogenesis.
Binding to mucin is the initial step for enteropathogens to establish pathogenesis. An open reading frame, gbpA, of Vibrio vulnificus was identified and characterized in this study. Compared with wild type, the gbpA mutant was impaired in binding to mucin-agar and the mucin-secreting HT29-methotrexate cells, and the impaired mucin binding was restored by the purified GbpA provided exogenously. ...
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ژورنال
عنوان ژورنال: FEMS Microbiology Letters
سال: 1999
ISSN: 0378-1097,1574-6968
DOI: 10.1111/j.1574-6968.1999.tb13570.x